Press Release Summary = Doctor Phaichit Warachit, the Director-General of Medical Sciences, said in a disclosure that the Ministry of Public Health, represented by the Department of Medical Sciences, had conducted a preliminary study of the toxicity of medicinal herb Pueraria mirifica the past period of seven months for consumer protection. The study in the first phase had now been completed, which was a study in white mice of both sexes by giving oral Pueraria mirifica powder at 1,000 milligrams per 1 kilogram of the mouse weight for 3 successive months compared with the control group receiving water.
Press Release Body = Pueraria Mirifica Test Finds No Cancer
Doctor Phaichit Warachit, the Director-General of Medical Sciences, said in a disclosure that the Ministry of Public Health, represented by the Department of Medical Sciences, had conducted a preliminary study of the toxicity of medicinal herb Pueraria mirifica the past period of seven months for consumer protection. The study in the first phase had now been completed, which was a study in white mice of both sexes by giving oral Pueraria mirifica powder at 1,000 milligrams per 1 kilogram of the mouse weight for 3 successive months compared with the control group receiving water.
Bangkok Thailand 12/13/2005
Pueraria Mirifica Test Finds No Cancer Doctor Phaichit Warachit, study the toxicity Pueraria mirifica the past period seven months for consumer protection. The study in the first phase had now been completed, which was a study in white mice of both sexes by giving oral Pueraria mirifica powder at 1,000 milligrams per 1 kilogram of the mouse weight for 3 successive months compared with the control group receiving water.
As the outcome of the study it was found that the dose of 10 mg/kg/day of Pueraria mirifica did not bring about an irregularity of blood cells of various kinds and chemicals in blood, including not bringing about an irregularity of the internal organs, while the mice receiving the dose of 100 mg/kg/day of Pueraria mirifica had a decline in growth and eating; no irregularity of blood cells of various kinds was found, but the protein content in the male mice decreased, while in the female mice the uterus was found having a increasing weight, but no irregularity of the uterine cells was found.
Meanwhile, the dose of 1,000 mg/kg/day of Pueraria mirifica caused the growth and eating of the mice to decrease; the number of red corpuscles decreased in the mice of both sexes. In the male mice there was a decrease of one-third in white corpuscles and granules; there was blood congestion at the testicles while in the female mice it caused the uterus to have and increasing weight. but no irregularity of the uterine cells different from the control group was found.
The above study outcome points out that the dose of 10 mg/kg/day of Pueraria mirifica does not cause toxicity to arise in the experimental animals, while the dose of 100 mg/kg/day generates some irregularities in the white mice, so the Department of medical Sciences proposes that the dose of Pueraria mirifica likely to be safe in the Thais, whose average weight is about 50 kilograms, should be one not exceeding 50-100 mg/day, given that human beings are about 5-10 times more sensitive to toxicity than mice.
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